diff --git a/Makefile b/Makefile
index 03daa184c..f2444120a 100644
--- a/Makefile
+++ b/Makefile
@@ -40,6 +40,7 @@ TARGETS := \
 	testdata/fwd_decl \
 	testdata/kconfig \
 	testdata/kconfig_config \
+	testdata/ksym \
 	testdata/kfunc \
 	testdata/invalid-kfunc \
 	testdata/kfunc-kmod \
diff --git a/btf/btf.go b/btf/btf.go
index ff9fe4d95..880c5ade0 100644
--- a/btf/btf.go
+++ b/btf/btf.go
@@ -443,13 +443,19 @@ func fixupDatasec(types []Type, sectionSizes map[string]uint32, offsets map[symb
 		// Some Datasecs are virtual and don't have corresponding ELF sections.
 		switch name {
 		case ".ksyms":
-			// .ksyms describes forward declarations of kfunc signatures.
+			// .ksyms describes forward declarations of kfunc signatures, as well as
+			// references to kernel symbols.
 			// Nothing to fix up, all sizes and offsets are 0.
 			for _, vsi := range ds.Vars {
-				_, ok := vsi.Type.(*Func)
-				if !ok {
-					// Only Funcs are supported in the .ksyms Datasec.
-					return fmt.Errorf("data section %s: expected *btf.Func, not %T: %w", name, vsi.Type, ErrNotSupported)
+				switch t := vsi.Type.(type) {
+				case *Func:
+					continue
+				case *Var:
+					if _, ok := t.Type.(*Void); !ok {
+						return fmt.Errorf("data section %s: expected %s to be *Void, not %T: %w", name, vsi.Type.TypeName(), vsi.Type, ErrNotSupported)
+					}
+				default:
+					return fmt.Errorf("data section %s: expected to be either *btf.Func or *btf.Var, not %T: %w", name, vsi.Type, ErrNotSupported)
 				}
 			}
 
diff --git a/elf_reader.go b/elf_reader.go
index eb7f03319..6887f819d 100644
--- a/elf_reader.go
+++ b/elf_reader.go
@@ -15,6 +15,7 @@ import (
 	"github.com/cilium/ebpf/asm"
 	"github.com/cilium/ebpf/btf"
 	"github.com/cilium/ebpf/internal"
+	"github.com/cilium/ebpf/internal/kallsyms"
 	"github.com/cilium/ebpf/internal/sys"
 )
 
@@ -32,6 +33,14 @@ type kfuncMeta struct {
 	Func    *btf.Func
 }
 
+type ksymMetaKey struct{}
+
+type ksymMeta struct {
+	Binding elf.SymBind
+	Addr    uint64
+	Name    string
+}
+
 // elfCode is a convenience to reduce the amount of arguments that have to
 // be passed around explicitly. You should treat its contents as immutable.
 type elfCode struct {
@@ -44,6 +53,7 @@ type elfCode struct {
 	maps     map[string]*MapSpec
 	vars     map[string]*VariableSpec
 	kfuncs   map[string]*btf.Func
+	ksyms    map[string]uint64
 	kconfig  *MapSpec
 }
 
@@ -136,6 +146,7 @@ func LoadCollectionSpecFromReader(rd io.ReaderAt) (*CollectionSpec, error) {
 		maps:        make(map[string]*MapSpec),
 		vars:        make(map[string]*VariableSpec),
 		kfuncs:      make(map[string]*btf.Func),
+		ksyms:       make(map[string]uint64),
 	}
 
 	symbols, err := f.Symbols()
@@ -627,6 +638,8 @@ func (ec *elfCode) relocateInstruction(ins *asm.Instruction, rel elf.Symbol) err
 		}
 
 		kf := ec.kfuncs[name]
+		ksymAddr := ec.ksyms[name]
+
 		switch {
 		// If a Call / DWordLoad instruction is found and the datasec has a btf.Func with a Name
 		// that matches the symbol name we mark the instruction as a referencing a kfunc.
@@ -647,6 +660,16 @@ func (ec *elfCode) relocateInstruction(ins *asm.Instruction, rel elf.Symbol) err
 
 			ins.Constant = 0
 
+		case ksymAddr != 0 && ins.OpCode.IsDWordLoad():
+			if bind != elf.STB_GLOBAL && bind != elf.STB_WEAK {
+				return fmt.Errorf("asm relocation: %s: %w: %s", name, errUnsupportedBinding, bind)
+			}
+			ins.Metadata.Set(ksymMetaKey{}, &ksymMeta{
+				Binding: bind,
+				Name:    name,
+				Addr:    ksymAddr,
+			})
+
 		// If no kconfig map is found, this must be a symbol reference from inline
 		// asm (see testdata/loader.c:asm_relocation()) or a call to a forward
 		// function declaration (see testdata/fwd_decl.c). Don't interfere, These
@@ -1280,8 +1303,18 @@ func (ec *elfCode) loadKsymsSection() error {
 	}
 
 	for _, v := range ds.Vars {
-		// we have already checked the .ksyms Datasec to only contain Func Vars.
-		ec.kfuncs[v.Type.TypeName()] = v.Type.(*btf.Func)
+		switch t := v.Type.(type) {
+		case *btf.Func:
+			ec.kfuncs[t.TypeName()] = t
+		case *btf.Var:
+			ec.ksyms[t.TypeName()] = 0
+		default:
+			return fmt.Errorf("unexpected variable type in .ksysm: %T", v)
+		}
+	}
+
+	if err := kallsyms.LoadSymbolAddresses(ec.ksyms); err != nil {
+		return fmt.Errorf("error while loading ksym addresses: %w", err)
 	}
 
 	return nil
diff --git a/elf_reader_test.go b/elf_reader_test.go
index 0d5408ecd..af352d643 100644
--- a/elf_reader_test.go
+++ b/elf_reader_test.go
@@ -14,6 +14,7 @@ import (
 
 	"github.com/cilium/ebpf/btf"
 	"github.com/cilium/ebpf/internal"
+	"github.com/cilium/ebpf/internal/kallsyms"
 	"github.com/cilium/ebpf/internal/linux"
 	"github.com/cilium/ebpf/internal/sys"
 	"github.com/cilium/ebpf/internal/testutils"
@@ -772,6 +773,62 @@ func TestKconfigConfig(t *testing.T) {
 	qt.Assert(t, qt.Not(qt.Equals(value, 0)))
 }
 
+func TestKsym(t *testing.T) {
+	file := testutils.NativeFile(t, "testdata/ksym-%s.elf")
+	spec, err := LoadCollectionSpec(file)
+	qt.Assert(t, qt.IsNil(err))
+
+	var obj struct {
+		Main     *Program `ebpf:"ksym_test"`
+		ArrayMap *Map     `ebpf:"array_map"`
+	}
+
+	err = spec.LoadAndAssign(&obj, nil)
+	testutils.SkipIfNotSupported(t, err)
+	qt.Assert(t, qt.IsNil(err))
+	defer obj.Main.Close()
+	defer obj.ArrayMap.Close()
+
+	_, _, err = obj.Main.Test(internal.EmptyBPFContext)
+	testutils.SkipIfNotSupported(t, err)
+	qt.Assert(t, qt.IsNil(err))
+
+	ksyms := map[string]uint64{
+		"socket_file_ops": 0,
+		"tty_fops":        0,
+	}
+
+	qt.Assert(t, qt.IsNil(kallsyms.LoadSymbolAddresses(ksyms)))
+
+	var value uint64
+	qt.Assert(t, qt.IsNil(obj.ArrayMap.Lookup(uint32(0), &value)))
+	qt.Assert(t, qt.Equals(value, ksyms["socket_file_ops"]))
+
+	err = obj.ArrayMap.Lookup(uint32(1), &value)
+	qt.Assert(t, qt.IsNil(err))
+	qt.Assert(t, qt.Equals(value, ksyms["tty_fops"]))
+}
+
+func TestKsymWeakMissing(t *testing.T) {
+	file := testutils.NativeFile(t, "testdata/ksym-%s.elf")
+	spec, err := LoadCollectionSpec(file)
+	qt.Assert(t, qt.IsNil(err))
+
+	var obj struct {
+		Main *Program `ebpf:"ksym_missing_test"`
+	}
+
+	err = spec.LoadAndAssign(&obj, nil)
+	testutils.SkipIfNotSupported(t, err)
+	qt.Assert(t, qt.IsNil(err))
+	defer obj.Main.Close()
+
+	res, _, err := obj.Main.Test(internal.EmptyBPFContext)
+	testutils.SkipIfNotSupported(t, err)
+	qt.Assert(t, qt.IsNil(err))
+	qt.Assert(t, qt.Equals(res, 1))
+}
+
 func TestKfunc(t *testing.T) {
 	testutils.SkipOnOldKernel(t, "5.18", "kfunc support")
 	file := testutils.NativeFile(t, "testdata/kfunc-%s.elf")
diff --git a/internal/kallsyms/kallsyms.go b/internal/kallsyms/kallsyms.go
index 776c7a10a..721d69d03 100644
--- a/internal/kallsyms/kallsyms.go
+++ b/internal/kallsyms/kallsyms.go
@@ -3,6 +3,8 @@ package kallsyms
 import (
 	"bufio"
 	"bytes"
+	"errors"
+	"fmt"
 	"io"
 	"os"
 	"sync"
@@ -52,6 +54,8 @@ func FlushKernelModuleCache() {
 	kernelModules.kmods = nil
 }
 
+var errKsymIsAmbiguous = errors.New("ksym is ambiguous")
+
 func loadKernelModuleMapping(f io.Reader) (map[string]string, error) {
 	mods := make(map[string]string)
 	scanner := bufio.NewScanner(f)
@@ -72,3 +76,52 @@ func loadKernelModuleMapping(f io.Reader) (map[string]string, error) {
 	}
 	return mods, nil
 }
+
+func LoadSymbolAddresses(symbols map[string]uint64) error {
+	if len(symbols) == 0 {
+		return nil
+	}
+
+	f, err := os.Open("/proc/kallsyms")
+	if err != nil {
+		return err
+	}
+
+	if err := loadSymbolAddresses(f, symbols); err != nil {
+		return fmt.Errorf("error loading symbol addresses: %w", err)
+	}
+
+	return nil
+}
+
+func loadSymbolAddresses(f io.Reader, symbols map[string]uint64) error {
+	scan := bufio.NewScanner(f)
+	for scan.Scan() {
+		var (
+			addr   uint64
+			t      rune
+			symbol string
+		)
+
+		line := scan.Text()
+
+		_, err := fmt.Sscanf(line, "%x %c %s", &addr, &t, &symbol)
+		if err != nil {
+			return err
+		}
+		// Multiple addresses for a symbol have been found. Lets return an error to not confuse any
+		// users and handle it the same as libbpf.
+		if existingAddr, found := symbols[symbol]; existingAddr != 0 {
+			return fmt.Errorf("symbol %s(0x%x): duplicate found at address 0x%x %w",
+				symbol, existingAddr, addr, errKsymIsAmbiguous)
+		} else if found {
+			symbols[symbol] = addr
+		}
+	}
+
+	if scan.Err() != nil {
+		return scan.Err()
+	}
+
+	return nil
+}
diff --git a/internal/kallsyms/kallsyms_test.go b/internal/kallsyms/kallsyms_test.go
index 4e245a0eb..ac3be9e69 100644
--- a/internal/kallsyms/kallsyms_test.go
+++ b/internal/kallsyms/kallsyms_test.go
@@ -7,18 +7,21 @@ import (
 	"github.com/go-quicktest/qt"
 )
 
+var kallsyms = []byte(`0000000000000000 t hid_generic_probe	[hid_generic]
+00000000000000EA t writenote
+00000000000000A0 T tcp_connect
+00000000000000B0 B empty_zero_page
+00000000000000C0 D kimage_vaddr
+00000000000000D0 R __start_pci_fixups_early
+00000000000000E0 V hv_root_partition
+00000000000000F0 W calibrate_delay_is_known
+A0000000000000AA a nft_counter_seq	[nft_counter]
+A0000000000000BA b bootconfig_found
+A0000000000000CA d __func__.10
+A0000000000000DA r __ksymtab_LZ4_decompress_fast
+A0000000000000EA t writenote`)
+
 func TestKernelModule(t *testing.T) {
-	kallsyms := []byte(`0000000000000000 t hid_generic_probe	[hid_generic]
-0000000000000000 T tcp_connect
-0000000000000000 B empty_zero_page
-0000000000000000 D kimage_vaddr
-0000000000000000 R __start_pci_fixups_early
-0000000000000000 V hv_root_partition
-0000000000000000 W calibrate_delay_is_known
-0000000000000000 a nft_counter_seq	[nft_counter]
-0000000000000000 b bootconfig_found
-0000000000000000 d __func__.10
-0000000000000000 r __ksymtab_LZ4_decompress_fast`)
 	krdr := bytes.NewBuffer(kallsyms)
 	kmods, err := loadKernelModuleMapping(krdr)
 	qt.Assert(t, qt.IsNil(err))
@@ -37,3 +40,25 @@ func TestKernelModule(t *testing.T) {
 
 	qt.Assert(t, qt.Equals(kmods["nft_counter_seq"], ""))
 }
+
+func TestLoadSymbolAddresses(t *testing.T) {
+	b := bytes.NewBuffer(kallsyms)
+	ksyms := map[string]uint64{
+		"hid_generic_probe": 0,
+		"tcp_connect":       0,
+		"bootconfig_found":  0,
+	}
+	qt.Assert(t, qt.IsNil(loadSymbolAddresses(b, ksyms)))
+
+	qt.Assert(t, qt.Equals(ksyms["hid_generic_probe"], 0))
+	qt.Assert(t, qt.Equals(ksyms["tcp_connect"], 0xA0))
+	qt.Assert(t, qt.Equals(ksyms["bootconfig_found"], 0xA0000000000000BA))
+
+	b = bytes.NewBuffer(kallsyms)
+	ksyms = map[string]uint64{
+		"hid_generic_probe": 0,
+		"writenote":         0,
+	}
+	err := loadSymbolAddresses(b, ksyms)
+	qt.Assert(t, qt.ErrorIs(err, errKsymIsAmbiguous))
+}
diff --git a/linker.go b/linker.go
index 788f21b7b..1466bea6d 100644
--- a/linker.go
+++ b/linker.go
@@ -9,6 +9,7 @@ import (
 	"io/fs"
 	"math"
 	"slices"
+	"strings"
 
 	"github.com/cilium/ebpf/asm"
 	"github.com/cilium/ebpf/btf"
@@ -457,3 +458,38 @@ func resolveKconfigReferences(insns asm.Instructions) (_ *Map, err error) {
 
 	return kconfig, nil
 }
+
+func resolveKsymReferences(insns asm.Instructions) error {
+	var missing []string
+
+	iter := insns.Iterate()
+	for iter.Next() {
+		ins := iter.Ins
+		meta, _ := ins.Metadata.Get(ksymMetaKey{}).(*ksymMeta)
+		if meta == nil {
+			continue
+		}
+
+		if meta.Addr != 0 {
+			ins.Constant = int64(meta.Addr)
+			continue
+		}
+
+		if meta.Binding == elf.STB_WEAK {
+			// A weak ksym variable in eBPF C means its resolution is optional.
+			// Set a zero constant explicitly for clarity.
+			ins.Constant = 0
+			continue
+		}
+
+		if !slices.Contains(missing, meta.Name) {
+			missing = append(missing, meta.Name)
+		}
+	}
+
+	if len(missing) > 0 {
+		return fmt.Errorf("missing ksyms: %s", strings.Join(missing, ","))
+	}
+
+	return nil
+}
diff --git a/prog.go b/prog.go
index 983044c0c..98c11cba5 100644
--- a/prog.go
+++ b/prog.go
@@ -337,6 +337,10 @@ func newProgramWithOptions(spec *ProgramSpec, opts ProgramOptions) (*Program, er
 	}
 	defer kconfig.Close()
 
+	if err := resolveKsymReferences(insns); err != nil {
+		return nil, fmt.Errorf("resolve .ksyms: %w", err)
+	}
+
 	if err := fixupAndValidate(insns); err != nil {
 		return nil, err
 	}
diff --git a/testdata/ksym-eb.elf b/testdata/ksym-eb.elf
new file mode 100644
index 000000000..5345cb759
Binary files /dev/null and b/testdata/ksym-eb.elf differ
diff --git a/testdata/ksym-el.elf b/testdata/ksym-el.elf
new file mode 100644
index 000000000..b9a7523d3
Binary files /dev/null and b/testdata/ksym-el.elf differ
diff --git a/testdata/ksym.c b/testdata/ksym.c
new file mode 100644
index 000000000..0f70d93bc
--- /dev/null
+++ b/testdata/ksym.c
@@ -0,0 +1,37 @@
+#include "common.h"
+
+char __license[] __section("license") = "Dual MIT/GPL";
+
+struct {
+	__uint(type, BPF_MAP_TYPE_ARRAY);
+	__uint(max_entries, 2);
+	__type(key, uint32_t);
+	__type(value, uint64_t);
+} array_map __section(".maps");
+
+extern void socket_file_ops __ksym;
+extern void tty_fops __ksym __weak;
+
+__section("socket") int ksym_test() {
+	uint32_t i;
+	uint64_t val;
+
+	i   = 0;
+	val = (uint64_t)&socket_file_ops;
+	bpf_map_update_elem(&array_map, &i, &val, 0);
+
+	i   = 1;
+	val = (uint64_t)&tty_fops;
+	bpf_map_update_elem(&array_map, &i, &val, 0);
+
+	return 0;
+}
+
+extern void non_existing_symbol __ksym __weak;
+
+__section("socket") int ksym_missing_test() {
+	if (&non_existing_symbol == 0) {
+		return 1;
+	}
+	return 0;
+}